In 2000, a national commitment has been made to expand access to antiretroviral (ARVs) in Vietnam. However, the number of patients infected with HIV in need of ARV has far exceeded the supply of ARVs. Little has been done on cost and effectiveness of antiretroviral treatment in Vietnam.
Prof. Chris Doran (University of Newcastle)
Prof. Peter Hill (University of Queensland)
Dr Anh Duc Ngo (University of South Australia)
A/Prof. David Wilson (University of New South Wales)
Dr Lei Zhang (University of New South Wales)
This PhD research will examine the costs and benefits of providing antiretroviral treatment in Vietnam. It will cover a range of specific aspects, including structural determinants of access to treatment, the cost-effectiveness of commencing antiretroviral treatment at different thresholds and the characteristics of patients who are lost to follow up.
The research will use a series of economic models to explore different aspects of the cost-effectiveness of treatment.
Papers:
Tran, D. A., Wilson, D. P., Shakeshaft, A.et al. Cost-Effectiveness of Antiretroviral Therapy Expansion strategies in Vietnam. AIDS Patient Care and STDs 28, 365-371, doi:10.1089/apc.2014.0016 (2014).
Tran, D. A., Wilson, D. P., Shakeshaft, A.et al. Determinants of virological failure after 1 year's antiretroviral therapy in Vietnamese people with HIV: findings from a retrospective cohort of 13 outpatient clinics in six provinces. Sexually Transmitted Infections 90, 538-544, doi:10.1136/sextrans-2013-051353 (2014).
Tran, D. A., Shakeshaft, A., Ngo, A. D.et al. Determinants of antiretroviral therapy initiation and treatment outcomes for people living with HIV in Vietnam. HIV clinical trials 14, 21-33 (2013).
Tran, D. A., Ngo, A. D., Shakeshaft, A.et al. Trends in and Determinants of Loss to Follow Up and Early Mortality in a Rapid Expansion of the Antiretroviral Treatment Program in Vietnam: Findings from 13 Outpatient Clinics. PLoS ONE 8, e73181, doi:10.1371/journal.pone.0073181 (2013).
Tran, D. A., Shakeshaft, A., Ngo, A. D.et al. Structural Barriers to Timely Initiation of Antiretroviral Treatment in Vietnam: Findings from Six Outpatient Clinics. PLoS ONE 7, e51289, doi:10.1371/journal.pone.0051289 (2012).
Rao, C., Osterberger, B., Anh, T. D.et al. Compiling mortality statistics from civil registration systems in Viet Nam: the long road ahead. Bulletin of the World Health Organization 88, 58-65, doi:10.2471/BLT.08.061630 (2010).
Presentations:
Dam Anh Tran received a scholarship to present her work at the International AIDS Conference in Washington DC in 2012, and International AIDS Society Conference in Kuala Lumpur in 2013.
The findings of the project will strengthen the evidence base required to develop appropriate and effective antiretroviral treatment in Vietnam given the resource limitations in Vietnam.