fbpx Investigating the relationships between alcohol and other drug use, mental health, early-life factors and life-course outcomes: integrative analyses of data from four Australasian cohort studies | NDARC - National Drug and Alcohol Research Centre

Investigating the relationships between alcohol and other drug use, mental health, early-life factors and life-course outcomes: integrative analyses of data from four Australasian cohort studies

image - Investigating The Relationships Between Alcohol And Other Drug Use Mental Health Early Life Factors And Life Course Outcomes
Tags:
Date Commenced:
01/2014
Expected Date of Completion:
12/2015
Project Supporters:

NHMRC

Drug Type:
Project Members: 
image - Richard Mattick
Honorary Visiting Professor
Ph 02 9385 0333
image - 1314150062 Hutchinson Delyse 12
Visiting Senior Lecturer
Ph 50148
image - 1314149357 Ed Silins 010
Dr Edmund Silins
Conjoint Lecturer
image - 1314158526 Wendy Swift 013
Dr Wendy Swift
Senior Lecturer
Project Main Description: 

This study will use a highly innovative approach to pool data from four large and long-running Australasian cohort studies to better understand the developmental precursors and psychosocial consequences of teen drinking behaviours. Findings will provide dramatically improved knowledge of the developmental pathways to teen and young adult drinking and a clearer picture of the total burden of disease attributable to alcohol in an Australasian setting.

Project Collaborators: External: 

Associate Professor John Horwood
University of Otago

Professor David Fergusson
University of Otago

Professor Jackob Najman
University of Queensland

Professor George Patton
University of Melbourne

Professor John Toumbourou
Deakin University

Dr Carolyn Coffey
Murdoch Childrens Research Institute, University of Melbourne

Dr Craig Olsson
Murdoch Childrens Research Institute, University of Melbourne

Dr Elizabeth Spry
Murdoch Childrens Research Institute, University of Melbourne

Associate Professor Raimondo Bruno
University of Tasmania

Dr Robert Tait
Curtin University

Dr Rohan Borschmann
Murdoch Childrens Research Institute, University of Melbourne

Dr Maria Plotnikova
University of Queensland

Dr George Youssef
Deakin University

Dr Denise Becker
Murdoch Childrens Research Institute, University of Melbourne

Dr Helena Romaniuk
Murdoch Childrens Research Institute, University of Melbourne

Rationale: 

Drinking excessively in teen and young adult years is an increasing phenomenon and concern. However, little is known of the antecedents of many of the drinking behaviours and of related problems, as existing studies focus on late adolescence with considerably less attention given to understanding the early precursors of teen drinking behaviours. Additionally, some patterns of antecedent behaviours and of teen drinking behaviours (e.g. extreme binging or abstinence) occur infrequently and cannot be reliably analysed statistically in single cohorts. This study will integrate data from multiple large cohorts to increase sample size and provide power to conduct analyses of the antecedents and consequences of excessive teen drinking. The project builds on the work of the Cannabis Cohort Research Consortium, whose members have successfully conducted longitudinal analyses using these four cohorts.

Aims: 

To establish the antecedents and developmental consequences of high risk and excessive teen drinking.

Design and Method: 

Researchers will undertake integrative analyses across four of the region’s largest and most mature longitudinal studies of child development, which together have approximately 10,000 participants:

  • The Australian Temperament Project (ATP)
  • The Christchurch Health and Development Study (CHDS)
  • The Mater Hospital and University of Queensland Study of Pregnancy (MUSP)
  • The Victorian Adolescent Health Cohort (VAHCS)
Progress/Update: 

Capacity-building data harmonisation workshopfor investigators conducted. Alcohol use variables harmonised across cohorts and integrated dataset expanded. Cohort-based working groups established and analyses in progress.  NHMRC Project Grant which builds on current work in development.

Output: 

Previous research by the group using the integrated dataset was published in Lancet Psychiatry (Silins et al., Young adult sequelae of adolescent cannabis use: an integrative analysis; Lancet Psychiatry 2014; 1: 286-93) and findings received widespread national and international print, radio, television and online media coverage. An invited paper is under review (Hutchinson et al., Viewpoint: How can data harmonisation benefit mental health research? An example of the Cannabis Cohorts Research Consortium (CCRC); Australian New Zealand Journal of Psychiatry, 2014).

Numerous papers are in preparation: (1) Patterns of alcohol use and the transition to first parenthood; (2) Patterns of alcohol use and violence/aggression; (3) Patterns of alcohol use and alcohol-related problems in adolescence and suicide attempt; (4) Young adult sequelae of adolescent alcohol use.

Published papers

Silins, E., Fergusson, DM., Patton, GC., Horwood, L John., Olsson, CA., Hutchinson, DM., Degenhardt, L., Tait, R., Borschmann, R., Coffey, C., Toumbourou, JW., Najman, J., Mattick, RP., for the Cannabis Cohorts Research Consortium. Adolescent substance use and educational attainment: An integrative data analysis comparing cannabis and alcohol from three Australasian cohorts. Lancet Psychiatry (2015, submitted).

Presentations (presenter underlined)

Silins, E., Fergusson, DM., Patton, GC., Horwood, L John., Olsson, CA., Hutchinson, DM., Degenhardt, L., Tait, R., Borschmann, R., Coffey, C., Toumbourou, JW., Najman, J., Mattick, RP., for the Cannabis Cohorts Research Consortium. Adolescent substance use and educational attainment: An integrative data analysis comparing cannabis and alcohol from three Australasian cohorts. College on Problems of Drug Dependence. Poster. Phoenix, AZ. 16th June 2015.

Silins, E., Fergusson, DM., Patton, GC., Horwood, L John., Olsson, CA., Hutchinson, DM., Degenhardt, L., Tait, R., Borschmann, R., Coffey, C., Toumbourou, JW., Najman, J., Mattick, RP., for the Cannabis Cohorts Research Consortium. Adolescent substance use and educational attainment: An integrative data analysis comparing cannabis and alcohol from three Australasian cohorts. NIDA International Forum. Poster. Phoenix, AZ. 15th June 2015.

Benefits: 

This project will be the first to bring together data from large, mature cohorts on the relationships between high risk and excessive teen alcohol use, other substance use, mental health and social development. 

Drug Type: 
Project Status: 
Completed