The role of psychostimulants in fatal stroke among young people

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Date Commenced:
10/2017
Expected Date of Completion:
10/2018
Drug Type:
Project Members: 
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Senior Lecturer
Ph +61283821575
Project Main Description: 

The study will examine all cases of fatal stroke in Australia amongst young people (<45 years) over the period 2009-2016 to determine the role of psychostimulants in these events.

Project Collaborators: External: 

Professor Johan Duflou
University of Sydney

Dr Sharlene Kaye
NSW Health

Aims: 

Stroke can be a catastrophic consequence of methamphetamine use. In recent work on methamphetamine-related death we documented 38 cases of methamphetamine-related stroke, 2.3% of all methamphetamine-related deaths. The role of methamphetamine, and other psychostimulants such as cocaine, in the overall causation of fatal stroke in Australia amongst young people (<45 years) is unknown.   

Aims: 1. Determine the proportion of cases of fatal stroke amongst people aged <45 years in which psychostimulants were present in the blood, 2009-2016; 2. Determine trends over the study period in the contribution of psychostimulant-related stroke to overall stroke amongst young people; 3. Determine the relative role of psychostimulants in overall ischaemic and haemorrhagic stroke amongst young people in Australia; 4. Determine the sites in the brain of strokes amongst cases of fatal psychostimulant-related stroke and other cases of stroke amongst young people.  

Design and Method: 

Examination of all cases of fatal stroke amongst young people in Australia recorded in the National Coronial Information System.

Benefits: 

The project will provide the first national data in the world on the contribution of psychostimulants to fatal stroke amongst young people.

Project Research Area: 
Drug Type: 
Project Status: 
Current