Tapentadol is a centrally acting opioid analgesic with dual mechanisms of action, specifically µ-opioid receptor agonist and noradrenaline reuptake inhibition. This dual action is thought to result in a lower dose required to produce a given level of analgesia.
Patterns of alcohol and drug use
This study will investigate the first online alcohol and substance use prevention program targeted at both students and their parents.
We have developed a multidisciplinary global consortium of researchers who can provide independent high-quality evidence regarding the scale of illicit drug use, harms, access to services at country, regional and global levels, and build capacity for better data in these areas.
The practices of diversion and misuse of pharmaceutical stimulants give serious cause for concern due to their potential to increase the risk of drug toxicity, dependence, and serious adverse health consequences. These practices may be particularly harmful among illicit psychostimulant users.
The study will examine all cases of fatal stroke in Australia amongst young people (<45 years) over the period 2009-2016 to determine the role of psychostimulants in these events.
The Australian National Advisory Council on Alcohol and Drugs (ANACAD) has funded NDARC to conduct a feasibility study for an early warning system (EWS) project, involving a data collection model that allows rapid triangulation of existing data to provide an early warning and current assessment o
With NSW having the largest GLBT community in Australia, it is important that responses to the problems faced by these populations (including a higher risk of drug use and mental health problems) are informed by research evidence.
Substance use amongst adolescents (those in the age group of 10-19) is an important public health issue in many countries of the region.
This project will conduct the first-ever outpatient RCT to test the efficacy, safety and cost-effectiveness of the pharmaceutical cannabinoid nabiximols (Sativex®) for treating cannabis dependence.